产品货号：
Z29801
中文名称：
WRN抗体
英文名称：
Anti-WRN Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-WRN Antibody |
| 指标别名 | WRN RecQ like helicase;RECQ3;RECQL2;RECQL3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,rat |
| 应用范围 | WB |
| 基因名称 | WRN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human WRN recombinant protein (Position:Q122-N240).Human WRN shares 84% amino acid (aa) sequence identity with mouse WRN. |
| 实际分子量 | 250KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Werner syndrome ATP-dependent helicase,also known as DNA helicase,RecQ-like type 3,is an enzyme that in humans is encoded by the WRN gene.This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases.DNA helicases are involved in many aspects of DNA metabolism,including transcription,replication,recombination,and repair.This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization.It possesses an intrinsic 3' to 5' DNA helicase activity,and is also a 3' to 5' exonuclease.Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing,this protein may be involved in the repair of double strand DNA breaks.Defects in this gene are the cause of Werner syndrome,an autosomal recessive disorder characterized by premature aging. |
| Uniprot ID | Q14191 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | Werner syndrome RecQ like helicase |
| 蛋白名全称 | Werner syndrome ATP-dependent helicase |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：WRN抗体，WRN多抗，Anti-WRN Antibody